Impact of Gold Nanoparticles in Blood Parameters in Treated Mice with Mammary Adenocarcinoma

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Nanotechnology may be able to create many new materials and devices with a vast range of applications, such as in nanomedicine, nanoelectronics, biomaterials energy production, and consumer products. In this study four groups of mice with mammary adenocarcinoma treatment intra injection with gold nanoparticles(GNP), radiation by diode laser and photothermal therapy (GNP plus radiation), so the fourth group leave as control positive. Blood samples collection from all groups and analyzed in different times for measure blood parameters which include Hb, PCV, MCV, RBCs, WBCs and MCHC. The results revealed that all the parameters measurement less than the normal rang which indicate to that GNP, radiation and photothermal therapy not have any effect on blood parameters.