Author's response to reviews Title: Impact On Mortality And Cancer Incidence Rates Of Using Random Invitation From Population Registers For Recruitment To Trials Authors:

Matthew Burnell (m.burnell@ucl.ac.uk) Aleksandra Gentry-Maharaj (a.gentry-maharaj@ucl.ac.uk) Andy Ryan (a.ryan@ucl.ac.uk) Sophia Apostolidou (s.apostolidou@ucl.ac.uk) Mariam Habib (m.habib@ucl.ac.uk) Jatinderpal Kalsi (j.k.kalsi@ucl.ac.uk) Steven Skates (sskates@partners.org) Mahesh Parmar (max.parmar@ctu.mrc.ac.uk) Mourad Seif (mseif@manchester.ac.uk) Nazar Amso (amsonn@Cardiff.ac.uk) Keith Godfrey (keith.godfrey@ghnt.nhs.uk) David Oram (david.oram@bartsandthelondon.nhs.uk) Jonathan Herod (jonathan.herod@lwh.nhs.uk) Karin Williamson (Karin.Williamson@nuh.nhs.uk) Howard Jenkins (Howard.Jenkins@derbyhospitals.nhs.uk) Tim Mould (tim.mould@uclh.org) Robert Woolas (r.woolas@btinternet.com) John Murdoch (j.murdoch@UHBristol.nhs.uk) Stephen Dobbs (Stephen.Dobbs@bch.n-i.nhs.uk) Simon Leeson (Simon.Leeson@nww-tr.wales.nhs.uk) Derek Cruikshank (Derek.Cruickshank@stees.nhs.uk) Stuart Campbell (profscampbell@hotmail.com) Lesley Fallowfield (l.j.fallowfield@sussex.ac.uk) Ian Jacobs (i.jacobs@ucl.ac.uk) Usha Menon (u.menon@ucl.ac.uk)