Identifying optimal heparin m anagement during cardiopulmonary bypass in obese patients

65-0215 Copyright 2016 European Society of Anaesthesiology. All rights reser RESULTS Obese patients received higher initial and total doses of heparin (P<0.0001). Plasma heparin concentrations were significantly higher in obese patients at each time point (P<0.001) and reached very high values after the initial bolus (5.90 vs. 4.48 IU ml , P<0.0001). The relationship between plasma heparin concentration and ACT after the initial bolus was not linear and followed an asymptotic regression curve. Haemoglobin concentration decreased intraoperatively to a greater extent in the obese group (P<0.001). No significant differences in postoperative bleeding or global transfusion requirements were observed.