Author’s response to reviews Title: Indwelling pleural catheters for malignancy-associated pleural effusion: report on a single centre’s ten years of experience Authors:

Title: Indwelling pleural catheters for malignancy-associated pleural effusion: report on a single centre’s ten years of experience Authors: Nikolaj Frost (nikolaj.frost@charite.de) Martin Brünger (martin.bruenger@charite.de) Christoph Ruwwe-Glösenkamp (christoph.ruwwe-gloesenkamp@charite.de) Antje Tessmer (antje.tessmer@t-online.de) Bettina Temmesfeld-Wollbrück (bettina.temmesfeld@charite.de) Dirk Schürmann (dirk.schuermann@charite.de) Norbert Suttorp (norbert.suttorp@charite.de) Martin Witzenrath (martin.witzenrath@charite.de) Version: 1 Date: 21 Jun 2019 Author’s response to reviews: Point-by-point reply to the reviewer’s comments We would like to thank the reviewers for the time and effort invested in reviewing our work. We appreciate the insightful comments and advice, which we have taken very seriously. Following the suggestions, we added further data. The constructive comments have helped us to further strengthen key aspects of the study and to underscore the validity of our findings. We are solidly confident that our revised manuscript will meet the high standards of the reviewers and readers of BMC Pulmonary Medicine.