Quick fire abstracts - session vi

RJ Eames,G Benedetti,C Torlasco, I Lobascio, L Ricketts, KE Keenan, R Bruehl, B Ittermann, J Jang, AS Flett, T Dresselaers,FP Mongeon, R Nezafat,P Kellman, LAE Brown, DA Broadbent, S Onciul, G Fent, J Foley,PG Chew, P Garg, K Knott, H Xue, JC Moon, S Plein, KRISTOPHER Knott,REDHA Boubertakh,MANISH Ramlall,VERONICA Culotta,CAMILLA Torlasco,STEFFEN Petersen, CHARLOTTE, Manisty,PETER Kellman,JAMES Moon

European Heart Journal - Cardiovascular Imaging(2017)

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摘要
092 Figure. Eur Heart J Cardiovasc Imaging Abstracts Supplement, 2017 doi:10.1093/ehjci/jex123 Published by Oxford University Press on behalf of the European Society of Cardiology 2017. J_ID: EJECHOCARD Customer A_ID: JEX123 Copyedited by: PR Manuscript Category: Cadmus Art: OP-EJEC1701 echocardiography and for a CMR study, respectively within 7 days after the event and 10 days after symptoms onset; high quality images. In 20 patients we measured 3D radial (GRS), circumferential (GCS) and longitudinal (GLS) echocardiographic strain. FT analysis was performed with Circle Cardiovascular Imaging Tissue Tracking, cvi42, Calgary, Alberta, Canada. Results: we evaluated 79 patients with GRS, GCS and GLS in 2D and 3D analysis using FT. We observed: a significant correlation between CMR ejection fraction (EF) and the peak values of each strain (r 0,80, p< 0,0001), and between the peak values and both late gadolinium enhancement percentage (LGE) and edema (strongest correlation between 2D-GCS and LGE%, r 0,66, p< 0,0001). Anterior segments showed the closest correlation between the peak systolic strain and the transmurality of the necrosis. In comparison with 3D echocardiographic strain parameters, Bland and Altman plots showed the existence of a trivial systematic difference between the measurements (narrowest limits of agreement for the 3D GLS). Conclusion: to our knowledge, our study is the first one which compares parameters of cardiac deformation using FT with CE-CMR findings. The validation of 3D FT strain against 3D echocardigraphic strain is reproducible for the GLS. Moreover, we found strong association between EF in CMR and emerging myocardial deformation measurements (i.e. peak systolic strain) by FT. Finally, we found a good correlation between necrosis transmurality and the peak systolic strain in segment per segment analysis. 095. EVALUATION OF MYOCARDIAL DEFORMATION BY TISSUETRACKING-CMR IN THE INDETERMINATE FORM OF CHAGAS DISEASE R PL ACIDO, AG Almeida, B Cunha Lopes, T Guimar~ aes, FJ Pinto, CE Rochitte Cardiology Department, Lisbon Academic Medical Centre, CCUL, Santa Maria University Hospital, Lisbon, PORTUGAL; Cardiovascular Magnetic Resonance and Computed Tomography Sector, Heart Institute, InCor, University of S~ ao Paulo, S~ ao Paulo, BRAZIL Objectives: Chagasic cardiomyopathy (CC) is characterized by progressive tissue destruction and fibrosis, being one of the main public health problems in South America. At present, early detection of cardiac involvement is limited by the absence of validated diagnostic criteria, particularly in the indeterminate form (IF) of the disease. The evaluation of myocardial deformation is an attractive method for the subclinical detection of ventricular dysfunction in several heart diseases. However, the role of cardiac magnetic resonance (CMR) imaging in its determination remains to be established. Objectives: Evaluation of left ventricular (LV) systolic deformation by CMR in patients with IF CC and its correlation with the presence of myocardial fibrosis. Methods: A retrospective observational study of IF CC patients undergoing CMR for evaluation of LV systolic dysfunction and quantification of fibrosis, compared to a normal control population (with age and genre). Results: Twenty-two patients with IF CC (60 6 8.8 years, 23% male) and 11 controls were included. There were no statistically significant differences in dimensional parameters and biventricular ejection fractions between the two groups. Significant differences were observed between the IF CC and control groups for the systolic global longitudinal strain (GLS) (-16.1 6 2.2% vs. -19.6 6 1.8%, p< 0.001). The presence of myocardial fibrosis was detected in 8% of the patients with IF CC (4.8 6 1.8% of the total myocardial mass of the LV). The presence of fibrosis was significantly correlated with systolic GLS (r1⁄4 0.74, p< 0.001), unrelated to other variables. Conclusion: Systolic GLS was significantly reduced in patients with IF CC and preserved LV ejection fraction, being correlated with the extent of myocardial fibrosis. This parameter should be routinely assessed when trying to early detect Chagasic cardiac involvement. 096. COMPARISON OF 3D STRESS CMR IMAGING WITH CT STRESS PERFUSION AND CORONARYANGIOGRAPHY IN HEART TRANSPLANT
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