Syddansk Universitet Tumor Necrosis Factor-Mediated Survival of CD169+ Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection Shinde,

Innate immune activation is essential to mount an effective antiviral response and to prime adaptive immunity. Although a crucial role of CD169 cells during vesicular stomatitis virus (VSV) infections is increasingly recognized, Received 19 September 2017 Accepted 1 November 2017 Accepted manuscript posted online 15 November 2017 Citation Shinde PV, Xu HC, Maney SK, Kloetgen A, Namineni S, Zhuang Y, Honke N, Shaabani N, Bellora N, Doerrenberg M, Trilling M, Pozdeev VI, van Rooijen N, Scheu S, Pfeffer K, Crocker PR, Tanaka M, Duggimpudi S, Knolle P, Heikenwalder M, Ruland J, Mak TW, Brenner D, Pandyra AA, Hoell JI, Borkhardt A, Häussinger D, Lang KS, Lang PA. 2018. Tumor necrosis factormediated survival of CD169+ cells promotes immune activation during vesicular stomatitis virus infection. J Virol 92:e01637-17. https://doi .org/10.1128/JVI.01637-17. Editor Bryan R. G. Williams, Hudson Institute of Medical Research Copyright © 2018 Shinde et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license. Address correspondence to Philipp A. Lang, langp@uni-duesseldorf.de. K.S.L. and P.A.L. contributed equally to this work. CELLULAR RESPONSE TO INFECTION