The Apical Constriction Force of Madin-Darby Canine Kidney (MDCK) Cells

Gustavo Campos, Tayana Tsubone,Vita Solovyeva,Jonathan Brewer, David Needham,Rosangela Itri, Aravind Rammohan, Cecile M. Bidan,Mario Fratzl,Philippe Moreau, Alain H. Lombard,Irene Wang,Martial Balland,Thomas Boudou,Nora M. Dempsey, Thibaut Devillers,Aurelie Dupont

semanticscholar（2018）

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摘要

mechanosensing studies. Specifically, the dBFP allows us to analyze dual receptor crosstalk by quantifying the spatiotemporal requirements and functional consequences of the upand down-stream signaling events. In this work, the utility and power of the dBFP has been demonstrated with four important dual receptor systems that play key roles in immunological synapse formation, shear-dependent thrombus formation, and agonist driven blood clotting respectively.

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