United States Patent ( 19 ) Sumiyoshi et al . 54 INFECTIOUS JAPANESE ENCEPHALITIS VIRUS CDNA CLONES THAT PRODUCE HGHLY ATTENUATED RECOMBINANT JAPANESE ENCEPHALITIS VIRUS

WACCNES THEREOF, Hideo Sumiyoshi, Branford, Conn,Charles H. Hoke

semanticscholar(2017)

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Kaluzovái et al. "Reverted Virulence of attenuated tick -borne encephalitis virus mutant is not accompanied with the changes in deduced viral envelope protein amino acid sequence” Acta Virologica 38: 133-140, 1994. Aihara et al., "Identification of Mutations That Occurred on the Genome of Japanese Encephalitis Virus During the Attenuation Process” Virus Genes 5: 95-109 (1991). Bowie et al., "Deciphering the Message in Protein Sequences: Tolerance to Amino Acid Substitutions" Science 237: 1306-1310 (Mar. 16, 1990). Davis et al., “Attenuating Mutations in the E2 Glycoprotein Gene of Venezuelan Equine Encephalitis Virus: Construc tion of Single and Multiple Mutants in a Full-Length cDNA Clone” Virology 183:20-31 (1991). Eckels et al., "Japanese encephalitis virus live-attenuated vaccine, Chinese strain SA-14-2; adaptation to primary canine kidney cell cultures and preparation of a vaccine for human use" Vaccine 6: 513-518 (1988). USOO5736148A
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