Bone marrow-derived CD 11 b + Jagged-2 + cells promote epithelial to mesenchymal transition and metastization in colorectal cancer

Angiogenesis Lab, CIPM, Portuguese Institute of Oncology, IPOLFG, EPE, Lisbon, Portugal; Gastroenterology Department, Portuguese Institute of Oncology, IPOLFG, EPE, Lisbon, Portugal; Histopathology Unit, Portuguese Institute of Oncology, IPOLFG, EPE, Lisbon, Portugal; 4 Division of Stem Cell Dynamics, Center for Stem Cell Biology & Regenerative Medicine, Institute of Medical Science, University of Tokyo, Japan; 5 Department of Immunology, Juntendo University School of Medicine, Japan; Laboratory of Stem Cell Regulation, Center for Stem Cell Biology & Regenerative Medicine, Institute of Medical Science, University of Tokyo, Japan; 7 Instituto Gulbenkian de Ciência, Oeiras, Portugal; Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Portugal.