1 BRK ” ing ” Down All We Know About PTK 6 in Breast Cancer 2

1 BRK”ing” Down All We Know About PTK6 in Breast Cancer 2 Yi Yuan1,2,#, Hui Li Ang1,2,#, Xianning Lai1, Lingzhi Wang1,2, Vijay Pandey1, Benjamin BoJun Huang1,2, 3 Tuan Zea Tan1, Hui Yi Chong1,2, Phillip Zheng-Yang Ong1,2, Kanchugarakoppal S. Rangappa3, Frank 4 Arfuso4, Kevin Shyong-Wei Tan5,6, Basappa3, Boon Cher Goh1,2,7,8, Ruby Yun-Ju Huang1,9,10 , Gautam 5 Sethi2,11,12, Peter E. Lobie1,13, Alan Prem Kumar1,2,8,11,14,* 6 Author's Affiliations: 7 1Cancer Science Institute of Singapore, National University of Singapore, Singapore 8 2Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 9 3Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore, India 10 4Stem Cell and Cancer Biology Laboratory, School of Biomedical Sciences, Curtin Health Innovation Research 11 Institute, Curtin University, Perth, Western Australia, Australia 12 5Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of 13 Singapore, Singapore 14 6NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore 15 7Department of Haematology-Oncology, National University Health System, Singapore 16 8National University Cancer Institute, National University Health System, Singapore 17 9Department of Obstetrics and Gynaecology, National University Health System, Singapore 119228, Singapore 18 10Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 19 11Cancer Program, Medical Science Cluster, Yong Loo Lin School of Medicine, National University of Singapore, 20 Singapore 21 Preprints (www.preprints.org) | NOT PEER-REVIEWED | Posted: 2 August 2018 doi:10.20944/preprints201808.0044.v1