Molecular cloning and transient expression in COS 7 cells of a novel human PDE 4 B cAMP-specific phosphodiesterase , HSPDE 4 B 3

*Division of Biochemistry and Molecular Biology, Wolfson Building, University of Glasgow, Glasgow G12 8QQ, Scotland, U.K., †CellTech Therapeutics Ltd., 216 Bath Road, Slough, Berks. SL1 4EN, U.K., ‡Department of Veterans Affairs Medical Center, 151M, and Huntsman Cancer Institute, Department of Oncologic Sciences and §Department of Medicine (Hematology/Oncology), University of Utah Health Sciences Center, 500 Foothill Blvd., Salt Lake City, UT 84148, U.S.A.