Dual PI3K/mTOR Inhibition Suppresses Tumor pO2 within Viable Tumor Assessed by F-MRI and Multispectral Analysis

Fig.2. (A) Mean ΔpO2 (day 3-day 0) in four tissue classes. (B) Mean ΔpO2 change in viable tumor (with std error). * p<0.05 vs control. # p<0.05, ## p<0.01 vs pre-tx. Dual PI3K/mTOR Inhibition Suppresses Tumor pO2 within Viable Tumor Assessed by F-MRI and Multispectral Analysis Yunzhou Shi, Jason Oeh, Jeffrey Eastham-Anderson, Sharon Yee, David Finkle, Franklin V. Peale, Jed Ross, Maj Hedehus, Nicholas van Bruggen, Rayna Venook, Sarajane Ross, Deepak Sampath, and Richard A. D. Carano Biomedical Imaging, Genentech Inc.(Roche Group), South San Francisco, CA, United States, Translational Oncology, Genentech Inc.(Roche Group), South San Francisco, CA, United States, Pathology, Genentech Inc.(Roche Group), South San Francisco, CA, United States