Prenatal exposures to paracetamol / acetaminophen and precursor aniline impair 1 masculinisation of male brain and behaviour 2 3

Prenatal exposures to paracetamol/acetaminophen and precursor aniline impair 1 masculinisation of male brain and behaviour 2 3 Anders Hay-Schmidt 1 , Olivia T. Ejlstrup Finkielman 1 , Benjamin A.H. Jensen 2 , Christine F. 4 Høgsbro 2 , Jacob Bak Holm 2 , Kristoffer Haurum Johansen 2 , Tina Kold Jensen 3 , Anderson Martino 5 Andrade 4 , Shanna H. Swan 5 , Carl-Gustaf Bornehag 5,6 , Søren Brunak 8 , Bernard Jegou 7,9 , Karsten 6 Kristiansen 2 , David Møbjerg Kristensen 7,8 * 7 8 9 1 Department of Neuroscience and Pharmacology, Faculty of Health and Medical Sciences, 10 University of Copenhagen, Copenhagen, Denmark. 11 2 Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark. 12 3 Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, 13 Denmark. 14 4 Department of Physiology, Universidade Federal do Paraná, Curitiba, Brazil. 15 5 Department of Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York City, 16 USA. 17 6 Department of Health Sciences, Karlstad University, Karlstad, Sweden. 18 7 Inserm (Institut national de la santé et de la recherche médicale), IRSET, U1085, Rennes, France 19 8 Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, 20 Denmark. 21 9 EHESP-School of Public Health, Rennes, France 22 23