Dehydrated Amniotic Allograft Seeded with Stem Cells: The Clinical Perspectives for Wound Healing

Amniotic membrane is the inner most layer of the placenta; it has unique properties of the smooth proliferation of epithelial cells and contains many different growth factors and cytokines. Amniotic membrane transformation is currently being used for continuously widening the spectrum of regenerative medicine. It gets wide spread attention as an effective method of reconstruction and rejuvenation. Amniotic membrane can be processed to produce dehydrated human amnion membrane allograft (dHAM). This allograft has shown its efficacy in wound healing due to its inherited properties and balanced biological structure. It is a very easy to use and less painful supplement to the traditional wound healing procedure. In the present study, the dHAM structure, primary cytokines functions, viability of seeded WJ-MSCs on dHAM are evaluated. Besides, the competence compared with fresh amniotic membrane and the current clinical usages in wound healing applications are summarized.