Supporting Information Mitochondrial toxicity of organic arsenical: membrane permeability transition pore opening and respiratory dysfunction

Scheme S1. The molecular structure of organic arsenical MOPIMP. Figure S1. The collapse of membrane potential in isolated mitochondria. Figure S2. The release of cytochrome c from isolated mitochondria treated with different concentrations of compound MOPIMP. Figure S3. Increase of the mitochondrial membrane fluidity. After treated with compound MOPIMP, the drop of anisotropy r demonstrated the increase of membrane fluidity. The experiment was repeated more than three times. Figure S4. The lipid peroxidation induced by compound MOPIMP. Table S1. Influence of organic arsenical MOPIMP on mitochondrial metabolism parameters a