The selective p 38 inhibitor SB-239063 protects primary neurons from 2 mild to moderate excitotoxic injury 3

5 In Vivo Pharmacology, High Throughput Biology, Discovery Research, GlaxoSmithKline, PO Box 1539, Mail Code UW 2523, 709 Swedeland Road, 6 King of Prussia, PA 19406, USA 7 Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA 8 Neurology Centre of Excellence for Drug Discovery, GlaxoSmithKline, Harlow, UK 9 Cardiovascular and Urogenital Center of Excellence for Drug Discovery, GlaxoSmithKline, King of Prussia, PA, USA 10 11 Received 5 April 2002; received in revised form 23 May 2002; accepted 24 May 2002