Bioengineering the Lung : Molecules , Materials , Matrix , Morphology , and Mechanics A mathematical model to predict protein wash out kinetics during whole-lung lavage in autoimmune pulmonary alveolar proteinosis

Keiichi Akasaka, Takahiro Tanaka, Takashi Maruyama, Nobutaka Kitamura, Atsushi Hashimoto, Yuko Ito, Hiroyoshi Watanabe, Tomoshige Wakayama, Takero Arai, Masachika Hayashi, Hiroshi Moriyama, Kanji Uchida, Shinya Ohkouchi, Ryushi Tazawa, Toshinori Takada, Etsuro Yamaguchi, Toshio Ichiwata, Masaki Hirose, Toru Arai, Yoshikazu Inoue, Hirosuke Kobayashi, and Koh Nakata Bioscience Medical Research Center, Niigata University Medical and Dental Hospital, Niigata, Japan; Disaster Prevention Research Institute, Kyoto University, Kyoto, Japan; Department of Respiratory Medicine, Dokkyo Medical University Koshigaya Hospital, Saitama, Japan; Department of Anesthesiology, Dokkyo Medical University Koshigaya Hospital, Saitama, Japan; Division of Respiratory Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan; Department of Anesthesiology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; Department of Respiratory Medicine, Tohoku University Graduate school of Medicine, Miyagi, Japan; Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan; Department of Respiratory and Allergy Medicine, Aichi Medical University, Aichi, Japan; Department of Pulmonary Medicine, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan; Clinical Research Center, NHO Kinki-Chuo Chest Medical Center, Osaka, Japan; and Graduate School of Medical Sciences, Kitasato University, Kanagawa, Japan