Novel Therapeutics in Renal Diseases Exocyst Sec 10 protects renal tubule cells from injury by EGFR / MAPK activation and effects on endocytosis

Ben Fogelgren,* Xiaofeng Zuo,* Janine M. Buonato, Aleksandr Vasilyev, Jeong-In Baek, Soo Young Choi, Maria F. Chacon-Heszele, Aurélien Palmyre, Noemi Polgar, Iain Drummond, Kwon Moo Park, Matthew J. Lazzara, and Joshua H. Lipschutz Departments of Anatomy, Biochemistry, and Physiology, University of Hawaii at Manoa, Honolulu, Hawaii; Department of Medicine, Medical University of South Carolina, Charleston, South Carolina; Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Pathology, Harvard Medical School, Boston, Massachusetts; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Departments of Medicine and Genetics, Harvard Medical School, Boston, Massachusetts; Department of Anatomy and BK21 Plus, Kyungpook National University School of Medicine, Junggu, Daegu, Republic of Korea; and Department of Medicine, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina