Evaluation of percutaneous coronary intervention with stenting of improvement of left ventricular function in patients with single vessel coronary artery disease

Introduction. LV function may improve after revascularation of coronary occlusions or using a significiant amout of medication. However the quality of life of every patient who is indicated with a acute coronary syndrom is not well characterized. Aim of the study. The purpose of the current study was to evaluate the effect of coronary stenting on systolic and diastolic LV function. Material and methods. We studied 98 patient with coronary artery disease , ages 42-86 years (mean 56.6 years) referred for PCI with stenting . Echocardiography was performed in all patients before and within 48 hours after PCI stenting. Results. From systolic indices : left ventricular EF (ejection fraction) significantly increased (from 42.55 % to 57.32 % p-value < 0,001), left ventricular Fs (fractional shortening) significantly increased (from 26.54% to 29.75%, pvalue <0,001) and left ventricular wall motion scoring index significantly reduced ( from 1.05 to 1.00, p value<0,001).From diastolic indicators : left ventricular E velocity increased significantly ( from 0.79 to 0.84 Cm/sec , p-value <0,001) , E/a ratio increased significantly (from 1.18 to 1.34, p value <0,001), left ventricular deceleration time had a significant reduction (from 230.33 to 219.42 msec, p value <0.001) and left ventricular IVRT decreased significantly ( from 84.74 to 79.2 p value < 0.001). Conclusions. In this study, significant improvement in systolic and diastolic left ventricular function after angioplasty stenting were observed.