1 1 2 Flucytosine antagonism of azole activity versus Candida glabrata : 3 Role of transcription factor Pdr 1 and multidrug transporter Cdr

9 10 Department of Microbiology and Immunology, Drexel University College of Medicine, 11 Philadelphia, Pennsylvania, 1 and Femeris Women’s Health Research Center, Medical Diagnostic 12 Laboratories, Hamilton, New Jersey 2 13 14 15 Running title: FLUCYTOSINE-AZOLE ANTAGONISM IN CANDIDA GLABRATA 16 17 18 * Corresponding author. Mailing address: Department of Microbiology and Immunology, Drexel 19 University College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129. Phone: (215) 991-8337. 20 Fax: (215) 848-2271. E-mail: santosh.katiyar@drexelmed.edu 21 22 AAC Accepts, published online ahead of print on 26 August 2013 Antimicrob. Agents Chemother. doi:10.1128/AAC.02394-12 Copyright © 2013, American Society for Microbiology. All Rights Reserved.