Volumetric Accuracy and Parameter dependencies of MR Brain Tissue Model

Previous work has investigated the accuracy of estimating the pure tissue mean parameters [7] and described a method of improving parameter estimates based on regional partitioning of the images. In this current work, we wish to gain insight into the accuracy of volumetric estimates of each tissue class based on the known accuracies of the full parameter set of the pure tissue distributions. The predominant dependency between errors on each tissue class volume estimate and the errors in the model parameters is identified.