Supporting Information CF2H as hydrogen bond donor group for the fine tuning of peptide bond geometry with difluoromethylated pseudoprolines

3.1. (2S,4S)-2-DIFLUOROMETHYLOXAZOLIDINE-4-CARBOXYLIC ACID BENZYL ESTERS (S,S)-1 ......................................................... 10 3.2. (2R,4S)-2-DIFLUOROMETHYLOXAZOLIDINE-4-CARBOXYLIC ACID BENZYL ESTERS (R,S)-1 ........................................................ 12 3.3. (2S,4S)-N-ACETYL-2-DIFLUOROMETHYLOXAZOLIDINE-4-CARBOXYLIC BENZYL ESTER (S,S)-2 ................................................... 14 3.4. (2R,4S)-N-ACETYL-2-DIFLUOROMETHYLOXAZOLIDINE-4-CARBOXYLIC BENZYL ESTER (R,S)-2 ................................................... 16 3.5. (2S,4S)-N-ACETYL-2-DIFLUOROMETHYLOXAZOLIDINE-4-CARBOXYLIC ACID (S,S)-3 ................................................................ 18 3.6. (2R,4S)-N-ACETYL-2-DIFLUOROMETHYLOXAZOLIDINE-4-CARBOXYLIC ACID (R,S)-3 ............................................................... 20 3.7. (2S,4S)-N-ACETYL-2-DIFLUOROMETHYLOXAZOLIDINE-4-N-METHYLAMIDE (S,S)-4 ................................................................ 22 3.8. (2R,4S)-N-ACETYL-2-DIFLUOROMETHYLOXAZOLIDINE-4-N-METHYLAMIDE (R,S)-4 ............................................................... 24 3.9. FMOC-GLY-(2S,4S)-SER(PRO)-OBN 5A ............................................................................................................. 26 3.10. FMOC-GLY-(2R,4S)-SER(PRO)-OBN 5B ............................................................................................................. 28 3.11. FMOC-L-ALA-(2S,4S)-SER(PRO)-OBN 6A ........................................................................................................... 30 3.12. FMOC-L-ALA-(2R,4S)-SER(PRO)-OBN 6B ........................................................................................................... 32 3.13. FMOC-L-ALA-(2S,4S)-SER(PRO)-L-ALA-OTBU 7A ................................................................................................ 34 3.14. FMOC-L-ALA-(2R,4S)-SER(PRO)-L-ALA-OTBU 7B ................................................................................................ 36