The common variant of rs6214 in insulin like growth factor 1 ( IGF1 ) gene: a potential protective factor for non-alcoholic fatty liver disease.

Mohammad Sabzikarian,Touraj Mahmoudi,Seidamir Pasha Tabaeian,Gholamreza Rezamand,Asadollah Asadi,Hamid Farahani,Hossein Nobakht,Reza Dabiri,Fariborz Mansour-Ghanaei,Faramarz Derakhshan,Mohammad Reza Zali

Archives of physiology and biochemistry（2023）

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摘要

To our knowledge, these findings suggest, for the first time, that the rs6214 "A" allele and "AA + AG" genotype have protective effects for NAFLD susceptibility. Nonetheless, further studies are needed to validate our findings.

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关键词

IGF1,IGFBP3,insulin,non-alcoholic fatty liver disease,polymorphism

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