PIK3CA mutation and CNV status and post-chemoradiotherapy survival in patients with cervical cancer

Gynecologic Oncology(2020)

引用 14|浏览49
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摘要
•PIK3CA gene mutations and PI3K/AKT pathway aberrations are common in cervical cancer.•PIK3CA mutations and CNV status in cervical cancer correlated with outcomes after curative intent chemoradiotherapy.•Stratification of PIK3CA by copy number variation and somatic mutational status should be investigated further.
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关键词
PIK3CA,PI3K,AKT,MTOR,Cervical cancer
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