Modeling UBQLN2-mediated Neurodegenerative Disease in Mice: Shared and Divergent Properties of Wild Type and Mutant UBQLN2 in Phase Separation, Subcellular Localization, Altered Proteostasis Pathways, and Selective Cytotoxicity
Neurobiology of Disease(2020)
Key words
Proteostasis,Ubiquilin,Ubiquitin proteasome system,Amyotrophic lateral sclerosis,Frontotemporal dementia,Protein aggregation,Neurodegeneration
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