Implications of stx loss for clinical diagnostics of Shiga toxin-1 producing Escherichia coli 2 3

1. Dpt of Multidisciplinary Laboratory Science and Medical Biochemistry, Genetic Unit, 13 Akershus University Hospital, Norway, and Dpt of Life Sciences and Health, Oslo 14 Metropolitan University, Norway 15 2. Department of Zoonotic, Foodand Waterborne Infections, Norwegian Institute of Public 16 Health, Norway 17 3. Dpt of Chemistry, Biotechnology and Food Sciences, Norwegian University of Life 18 Sciences, Norway 19 4. Dpt of Microbiology and Infection control, Akershus University Hospital, Norway 20 5. Dpt of Life Sciences and Health, Oslo Metropolitan University 21 6. Dpt of Life Sciences and Health, Oslo Metropolitan University, Norway and Dpt of 22 Microbiology and Infection control, Akershus University Hospital, Norway 23 24