Microbiome Changes in Healthy Volunteers Treated with GSK 1322322 , a Novel Antibiotic Targeting Bacterial Peptide

Seda Arat, Aaron Spivak, Stephanie Van Horn, Elizabeth Thomas, Christopher Traini, Ganesh Sathe, George P. Livi, Karen Ingraham, Lori Jones, Kelly Aubart, David J. Holmes, Odin Naderer,* James R. Brown Computational Biology, GSK R&D, Collegeville, Pennsylvania, USA; Department of Mathematics, Virginia Tech, Blacksburg, Virginia, USA; Target and Pathway Validation, GSK R&D, Collegeville, Pennsylvania, USA; Antibacterial Discovery Performance Unit, GSK R&D, Collegeville, Pennsylvania, USA; Antibacterial Discovery Performance Unit, GSK R&D, Research Triangle Park, North Carolina, USA