Comprehensive Analysis of LRRK2 Mutation Carriers in Parkinson’s Disease with the TruSeq Neurodegeneration Panel
semanticscholar（2018）
摘要
Parkinson’s disease (PD) is a complexmultifactorial neurodegenerative disease, affecting an estimated 7–10 million people worldwide.1PD is caused by an interplay of genetic, environmental, and epigenetic factors. Known genetic factors associated with PD include 18 chromosomal locations, termed PARK (to denote their putative link to PD) 1-18,2 and 28 common variants across 24 loci that act as risk factors for sporadic disease.3
更多查看译文
AI 理解论文
溯源树
样例
生成溯源树，研究论文发展脉络
Chat Paper
正在生成论文摘要