In vitro and in vivo assessment of phage therapy against Staphylococcus aureus causing bovine mastitis.

C Ngassam-Tchamba,J N Duprez, M Fergestad,A De Visscher, T L'Abee-Lund,S De Vliegher,Y Wasteson,F Touzain, Y Blanchard,R Lavigne,N Chanishvili, D Cassart,J Mainil,D Thiry

Journal of Global Antimicrobial Resistance（2020）

引用 24|浏览10

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摘要

•Lytic activities of three bacteriophages in vitro against bovine mastitis Staphylococcus aureus.•Survival rate below 50% in vivo at DPI 4 with Galleria mellonella larvae.•Incomplete recovery of the mouse mastitis in vivo at HPI 48.•Significant differences after blending of larvae and mice mammary glands.

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关键词

Phage therapy,Staphylococcus aureus,Bovine mastitis

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