Circulating Angiogenic Cells (Cacs) In Glioblastoma: Towards Defining Crucial Functional Differences In Cac-Induced Neoplastic Versus Reactive Neovascularization

Our findings indicate that CAC-mediated neovascularization in GBM is characterized by more efficient CAC homing to target tissue and a more potent proangiogenic response than in physiologic tissue repair in MI. Our findings can aid in selecting targets for therapeutic strategies acting against GBM-specific CACs.