Gliomas display distinct sex-based differential methylation patterns based on molecular subtype.

Mette L Johansen,L C Stetson,Vachan Vadmal,Kristin Waite,Michael E Berens,James R Connor,Justin Lathia,Joshua B Rubin,Jill S Barnholtz-Sloan

Neuro-oncology advances（2020）

引用 16|浏览60

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摘要

DNA methylation differences between males and females in 4 glioma molecular subtypes suggest an important, sex-specific role for DNA methylation in epigenetic regulation of gliomagenesis.

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关键词

DNA methylation,glioblastoma,glioma,sex-specific differences,survival

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