Optimization of a syngeneic murine model of bone metastasis.

Henry P Farhoodi,Aude I Segaliny,Zachary W Wagoner,Jason L Cheng,Linan Liu,Weian Zhao

Journal of Bone Oncology（2020）

引用 5|浏览14

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摘要

•A method to generate bone metastases in over 95% of mice.•Tumors can be detected within one to two weeks.•Low rates of vital organ metastases, relative to other methods.•Consistent tumor localization in lower body.•Growth rate and consistency of tumors can be controlled by quantity of cancer cells injected.

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关键词

Cancer,Animal models,Bone metastasis,Intra-arterial, caudal artery,4T1

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