Finding the Sweet Spot: Parsing Tissue-Specific Contributions of Fructose Metabolism.
Cell Metabolism(2020)
摘要
The abundance of dietary sweeteners and overconsumption of fructose are widely thought to promote metabolic disease. In this issue of Cell Metabolism, Andres-Hernando et al. (2020) identify the liver as the major site of fructose metabolism-mediated metabolic dysfunction and identify a surprising role for intestinal fructose metabolism in driving fructose intake.
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