Synthesis and anti-proliferative activity of a novel 1,2,3-triazole tethered chalcone acetamide derivatives.
Bioorganic & Medicinal Chemistry Letters（2020）
摘要
A novel series of new building blocks consisting of 1,2,3-triazole tethered chalcone acetamides have been synthesized in excellent yields and evaluated for their anti-proliferative activity against four human cell lines. The docking results are complementary to the experimental observations.
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关键词
Chalcone,Acetamides,Cytotoxicity,Jones reagent,Growth inhibition,Human cancer cell lines
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