SARS-CoV-2 infections and COVID-19 mortalities strongly correlate with ACE1 I/D genotype

Naoki Yamamoto,Yasuo Ariumi,Nao Nishida,Rain Yamamoto,Georg Bauer,Takashi Gojobori,Kunitada Shimotohno,Masashi Mizokami

Gene（2020）

引用 110|浏览32

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摘要

•COVID-19 infection is characterized by its prominent effect on specific ethnic group.•SARS-CoV-2 cases/mortality were negatively associated with ACE1 II genotype.•The ACE1 II genotype could be a predictive marker of SARS-CoV-2 risk and severity.

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关键词

SARS-CoV-2,COVID-19,ACE,SARS,MERS,RAAS,I,D,bp,SNP,KPGP,FTP,SNV,VQSR,CTSL,TMPRSS2,gnomAD,Ang,ARDS,HLA

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