Pyroptosis: a pro-inflammatory type of cell death in cardiovascular disease.

Qun Wang,Jianfeng Wu, Yicheng Zeng,Kong Chen, Chuangxin Wang,Shiqi Yang, Nisi Sun,Hao Chen, Kang Duan,Gaofeng Zeng

Clinica Chimica Acta（2020）

引用 101|浏览16

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摘要

•Pyroptosis is a pro-inflammantory type of regulated cell death in CVD and gasdermin family is the effector.•Caspase-3/GSDME and caspase-8/GSDMD also can induce pyroptosis.•Targeting to pyroptosis-related pathway provides a promising research direction for the treatment and diagnosis of CVD.

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关键词

Pyroptosis,Caspase,Gasdermin family,Cardiovascular disease

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