Undetectable circulating tumor DNA levels correlate with low risk of recurrence/metastasis in postoperative pathologic stage I lung adenocarcinoma patients.

Weixiong Yang,Na You,Minghan Jia,Sai-Ching Jim Yeung,Wei Ou,Man Yu,Yinguang Wang,Xiayu Fu,Zhanfei Zhang,Jiali Yang,Zengding Lao,Zhenguo Liu,Bo Zeng,Qiuxiang Ou,Xue Wu,Yang W Shao,Xiaoyu Hong,Siyu Wang,Chao Cheng

Lung Cancer（2020）

引用 9|浏览14

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摘要

•Negative ctDNA may predict low risk of recurrence in operated stage I lung adenocarcinoma.•Whether ctDNA positive are more likely to relapse need further follow up to validate.•TP53 is associated with malignant progression in stage I lung adenocarcinoma.

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关键词

(p)Stage I lung adenocarcinoma,ctDNA monitoring,Ground-Glass opacity,Solid nodule,Next-Generation sequencing

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