IL-7 receptor alpha defines heterogeneity and signature of human effector memory CD8 + T cells in high dimensional analysis.
Cellular Immunology(2020)
摘要
•IL-7Rα has unique relationship with a set of molecules in EM CD8+ T cells.•Such a relationship defines heterogeneous cell subsets in EM CD8+ T cells.•Molecules expressed by these subsets may confer unique biological significance.
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关键词
EM,IL-7Rα or CD127,CyTOF,scRNA-seq,Th,R,PCA,t-SNE,DREMI,DREVI,PBMCs,DEGs,GZMB
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