Frontotemporal dementia: Plasma metabolomic signature using gas chromatography-mass spectrometry.

Anna Luiza Morais Santos,Jessica Gardone Vitório,Maria José Nunes de Paiva,Brenda Lee Simas Porto,Henrique Cerqueira Guimarães,Gisele André Baptista Canuto,Maria das Graças Carvalho,Leonardo Cruz de Souza,Juliano Simões de Toledo,Paulo Caramelli,Filipe Fideles Duarte-Andrade,Karina Braga Gomes

Journal of Pharmaceutical and Biomedical Analysis（2020）

引用 12|浏览16

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摘要

•bvFTD group presented an impairment of amino acid metabolism compared to controls.•bvFTD patients showed changes in translation process compared to controls.•bvFTD group did not present different metabolites compared to AD group.

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关键词

Frontotemporal dementia,Alzheimer’s disease,Metabolomic,Lipoperoxidation,Glutamatergic neurotransmission

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