Accelerating Development of SARS-CoV-2 Vaccines - The Role for Controlled Human Infection Models.

Meagan E Deming,Nelson L Michael,Merlin Robb,Myron S Cohen,Kathleen M Neuzil

The New England journal of medicine（2020）

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摘要

Controlled human infection models have been proposed as a strategy for accelerating SARS-CoV-2 vaccine development. But scientific and technical factors make CHIMs unlikely to accelerate the establishment of vaccine efficacy.

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