Maternal microbiome regulation prevents early allergic airway diseases in mouse offspring.

Jing Liu,Changli Tu,Jinyan Yu,Meizhu Chen,Cuiyan Tan,Xiaobin Zheng,Zhenguo Wang,Yingjian Liang,Kongqiu Wang,Jian Wu,Yanlei Li

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology（2020）

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摘要

This study presents a new framework for the prevention of childhood asthma, elucidating the mechanism of regulating the mother's intestinal microbiome to protect the offspring's early asthma via animal experiments.

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关键词

TLR2,TLR4,Tregs,allergic airway disease,asthma prevention,microbiome

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