False Rifampicin Resistance in Xpert Ultra Applied to Lymph Node Aspirate: A Case Report.

OPEN FORUM INFECTIOUS DISEASES(2020)

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摘要
A 36-year-old male patient was diagnosed with tuberculosis in Antwerp, Belgium, in May 2018. His lymph node aspirate initially tested rifampicin resistant in Xpert MTB/RIF Ultra, but tested susceptible in all other tests including targeted deep sequencing due to a rare matrix effect in the Xpert MTB/RIF Ultra reaction tube.
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关键词
extrapulmonary tuberculosis,false mutant melting temperature,false rifampicin resistance,lymph node,Xpert Ultra
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