Low bias DNA for sustainable and efficient data storage

Yanmin Gao
Yanmin Gao
Xin Chen
Xin Chen
Chengwei Zhang
Chengwei Zhang
Hongyan Qiao
Hongyan Qiao
Hao Qi
Hao Qi

bioRxiv, 2020.

Cited by: 0|Bibtex|Views38|Links

Abstract:

In DNA data storage, the huge sequence complexity is challenging for repeatable and efficient information reading from massive DNA oligo pool. Here, we demonstrated that synthetic oligo pool comprising over ten thousand strands was largely skewed by PCR process due to its inherent mechanism of inefficient priming, product-as-template, err...More

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