Sustainable DNA data storage with low biased manipulation

Yanmin Gao
Yanmin Gao
Xin Chen
Xin Chen
Chengwei Zhang
Chengwei Zhang
Hongyan Qiao
Hongyan Qiao
Hao Qi
Hao Qi

bioRxiv, pp. 1-28, 2020.

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Abstract:

In DNA data storage, the huge sequence complexity is challenging repeatable and efficient information reading. Here, we demonstrated that biased amplification is serious matter for stable information retrieve from synthetic oligo pool comprising over ten thousand strands encoding over 2.85 MB digital information. Therefore, we adapted iso...More

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