IQGAP1-dysfunction leads to induction of senescence in human vascular smooth muscle cells.

Wioleta Grabowska,Natalia Achtabowska,Agata Klejman,Krzysztof Skowronek,Małgorzata Całka,Anna Bielak-Zmijewska

Mechanisms of Ageing and Development（2020）

引用 5|浏览9

暂无评分

摘要

•IQGAP1 is present in cellular bridges wherein it co-localizes with actin.•Direct intercellular communication occurs preferentially between senescent cells.•IQGAP1 dysfunction can induce senescence.

查看译文

关键词

IQGAP1,Senescence,Intercellular communication,Cellular bridges (CBs),Tunneling nanotubes (TNTs),Vascular smooth muscle cells (VSMCs)

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要