Potential roles of Glucagon-like peptide-1 and its analogues in cognitive impairment associated with type 2 diabetes mellitus.

Zi-Wei Yu,Rong Liu,Xin Li,Ying Wang,Yu-Hong Fu,Hui-Yao Li,Yue Yuan,Xin-Yuan Gao

Mechanisms of Ageing and Development（2020）

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摘要

•Brain insulin resistance plays a major role in cognitive impairment in type 2 diabetes mellitus.•GLP-1 and its analogues can improve brain insulin resistance.•GLP-1 and its analogues can alleviate cognitive impairment in type 2 diabetes mellitus.

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关键词

Cognitive impairment,Glucagon-like peptide-1,Glucagon-like peptide-1 analogues,Type 2 diabetes mellitus

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