Turn Conformation of β-Amino Acid Based Short Peptides Promoted by an Amidothiourea Moiety at C-Terminus

Yanhan Zhang
Yanhan Zhang
Jinlian Cao
Jinlian Cao
Peimin Weng
Peimin Weng
Daiyu Miao
Daiyu Miao
Zhao Li
Zhao Li

The Journal of organic chemistry, 2020.

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Abstract:

C-terminal amidothiourea motif is shown to promote a β-turn like folded conformation in a series of β-amino acids based short peptides in both the solid state and solution phase, by an intramolecular 11-membered ring hydrogen bond.

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