Molecular surveillance of methicillin-resistant Staphylococcus aureus genomes in hospital unexpectedly reveals discordance between temporal and genetic clustering

Rebecca Rose,David J Nolan,Samual Moot,Christopher Rodriguez,Sissy Cross,Yvette S McCarter,Chad Neilsen,Susanna L Lamers

American Journal of Infection Control（2021）

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摘要

•WGS identified 7 Genetic Clusters of MRSA infections.•Genetically-related cases were observed up to 15 weeks apart.•Analysis revealed previously unidentified potential hospital source.•Hospital-source outbreaks were limited in scope.•None of the cases in 4 Temporal Clusters were genetically related.

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关键词

Clustering,Molecular epidemiology,Phylogenetics,Hospital-acquired infections,Whole genome sequencing

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