Recurrent Optic Neuritis in Children

• Cortical and diffuse MRI abnormalities were seen in some “Other” patients, such as 1 patient ultimately diagnosed with CNS vasculitis.• In the majority of cases, regardless of etiology, visual outcomes were good with at least 70% of eyes recovering to baseline 20/20 vision. This is similar to outcomes associated with MS-ON. 2• Some children with idiopathic recurrent ON may have Chronic Relapsing Inflammatory Optic Neuropathy (CRION), as described in adults. 3 High frequency of pain with eye movements and constricted visual fields are consistent with the description in adults.None of the authors have any conflict of interest related to this research. The Network of Pediatric MS Centers is supported by the National Multiple Sclerosis Society (NMSS) and the National Institute of Neurological Disorders and Stroke (NINDS) through the following grants: HC0165 and 1R01NS071463