Persisting SARS-CoV-2 viraemia after rituximab therapy: two cases with fatal outcome and a review of the literature.

Phil-Robin Tepasse,Wali Hafezi,Mathias Lutz,Joachim Kühn,Christian Wilms,Rainer Wiewrodt,Jan Sackarnd, Martin Keller,Hartmut H Schmidt,Richard Vollenberg

BRITISH JOURNAL OF HAEMATOLOGY（2020）

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摘要

SARS-CoV-2 infection can cause severe pneumonia (COVID-19). There is evidence that patients with comorbidities are at higher risk of a severe disease course. The role of immunosuppression in the disease course is not clear. In the present report, we first describe two cases of persisting SARS-CoV-2 viraemia with fatal outcome in patients after rituximab therapy.

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SARS-CoV-2,COVID-19,rituximab,viraemia,pneumonia

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